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Gamechangers

Get inspired by entrepreneur success stories, and learn from our insights into the rules of the road for building iconic companies.

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Human & Planetary Health

Get a look at the key themes that power our focus to improve human and planetary health and lead to zero carbon footprint societies. Some key areas include CRISPR-based and precision medicine platforms, new applications of neuroscience, new foods, new materials and more.

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Enterprise

Get a look at the key themes and drivers that power our full-stack enterprise investment focus including fostering human-assisted AI, leveraging the data economy, driving the developer-first era, leading the charge on cybersecurity, powering the renaissance of semiconductors and more.

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Consumer

Get a deep look at the key themes and trends that drive our consumer investment focus including new media platforms, the rebuilding of social media, trusted commerce platforms, marketplaces, sustainable and inclusive brands, the rise of the creator class, and more.

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Gamechangers

Get inspired by entrepreneur success stories, and learn from our insights into the rules of the road for building iconic companies.

View All

Enterprise

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Human & Planetary Health

View All

Consumer

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Our Learnings

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A library of our POVs across sectors and topics.

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Embrace the Future: Meet Your AI Teammates

Fund/Build/Scale: Understanding Privacy and Compliance (Transcript)

Fund/Build/Scale: Breaking in to Enterprise Sales (Transcript)

Fund/Build/Scale: Fundraising from Both Sides of the Table ...

What My Sports Movie Heroes Have Taught Me ...

Fund/Build/Scale: Tapping into the AI Developer Community (Transcript)

Cognition-as-a-Service (CaaS): The Rise of Digital Assistants & ...

Announcing the 2024 Mayfield Farmlink FIELD Fellows

Learnings from Leaders: Satya Nadella/Microsoft

Arvind Gupta on Innovation, Investing and Planetary Health

Fund/Build/Scale: Digging Your Moat: Customer Discovery + PLG ...

Partnering with Highway 9 Networks on Mobile Cloud ...

Introducing Fund/Build/Scale

Fund/Build/Scale: Navin Chaddha on Building Trust with Your ...

Scaling to $1M ARR and Beyond

Enduring Strategies for Inception-Stage Founders and Investors

Communicating Your Vision

Understanding Privacy and Compliance

Breaking in to Enterprise Sales

Tapping into the AI Developer Community

World Economic Forum: How AI Can Usher In ...

How to Take Your AI Startup from Research ...

Digging Your Moat: Customer Discovery + PLG for ...

Building Trust with Your Inception Investor

Fundraising from Both Sides of the Table

Alchemist Announces Backing from the Mayfield Fund

The Rise of the AI Cognitive Plumbing Layer

A People-First View of the AI Economy

Partnering with Sema4.ai to Accelerate the Agent Economy

Top 10 Takeaways From Davos

“No Rain, No Flowers: Funding Start-ups” Lessons From ...

Guru Pangal Joins Mayfield as a Venture Partner

Navin Chaddha Shares His Career Journey on the ...

2024 IT Priorities and Adoption of Gen AI

2023 Year in Review

Navigating the Good, the Bad, the Ugly of ...

Former TechCrunch Editor Launches New Podcast for AI ...

Arvind Gupta: Building Enduring Companies for Planetary Health

Partnering with Young Changemakers at Farmlink to Address ...

An Investor and a Practitioner’s Perspective on GenAI

Ursheet Parikh: Investing Ethically in AI and Synthetic ...

LLM-powered Developer Automation

From Inception to Iconic: What it Takes to ...

Navin Chaddha: Helping Entrepreneurs Achieve Their Dreams

What AI Will (& Won’t) Do: AI Predictions ...

Accelerating GenAI Adoption Through a Data Operations Cloud

Welcoming our First Dedicated Select/Spring Fund Partner Sri ...

A People-First View of the AI Economy | ...

Founding Voices: The Right Dose of Reality

Founding Voices: Dream Boldly, and Move with Purpose

5 Questions Investors Should be Asking Inception-stage Generative ...

Founding Voices: The Road is Longer Than You ...

Mayfield Announces $250 Million AI Start Seed Fund ...

Mayfield Launches New $250 Million AI-Specific Seed Stage ...

Announcing The $250 Million Mayfield AI Start Seed ...

Founding Voices: Embracing Serendipity

CRISPR+: The Next Generation CRISPR Systems and Applications ...

Built to Last – Where Will the Next ...

2023 Mid-year Review

Silicon Catalyst – Fireside Chat with Navin Chaddha

Founding Voices: Make Your Case to Transform the ...

The Golden Age of Semiconductor Innovation Continues

10 questions early-stage founders should be asking investors

Founding Voices: Clarity Creates Competence

MindsDB: Introducing the World’s First Cloud to Serve ...

Vartana lands a $20M investment to scale its ...

Auradine Raises $81 Million in Series A Financing ...