Mammoth - engineering biology start-up in Mayfield's portfolio

POV /

Human & Planetary Health

Endpoint - an Engineering Biology Start-up in Mayfield's Portfolio

POV /

Human & Planetary Health

We invest in exceptional people whose mission in life is to create a better world for our generation and the next ones.

We invest across the engineering biology innovation loop at the earliest stages of company building, primarily Seed and Series A. Since 1969, we have partnered with scores of legendary entrepreneurs and know that company building is a marathon, not a sprint. Learn more about our promise to entrepreneurs.

We have served as early investors to iconic biotech and healthIT entrepreneurs for over 50 years including Amgen, Genentech, Heartstream, Intuitive Surgical, Millennium Pharmaceuticals and Mammoth Biosciences. The ability to marry the engineering approaches of information technology with advances in biology will re-invent trillion dollar industries and transform human and planetary health. 

Reversing climate change and preserving humanity is the greatest task of our generation, and also presents the greatest entrepreneurial opportunity in history. By using biology as a technology to reinvent production of the food we eat, the clothes we wear and the places we live and work in, we have a path to zero carbon footprint societies.

Engineering Biology Pillars Graphic

POV

Viewpoint | Aug 29 2023

Founding Voices: Dream Boldly, and Move with Purpose

Human & Planetary Health | Founding Voices

Viewpoint | Jun 30 2023

CRISPR+: The Next Generation CRISPR Systems and Applications ...

Human & Planetary Health

Video | Jun 30 2023

Built to Last – Where Will the Next ...

Human & Planetary Health | Company Building

Viewpoint | Mar 22 2023

4 Insights from Investing in Windfall

Human & Planetary Health | News

Viewpoint | Dec 5 2022

Saving the World: The Playbook for Building Planetary ...

Human & Planetary Health

Article | Oct 4 2022

Bristol Myers Inks Protein Degrader Deal via Celgene ...

Human & Planetary Health | News

Viewpoint | Oct 4 2022

SyntheX and BMS Partner on Drug Development Deal ...

Human & Planetary Health | News

Entrepreneur Journey | Oct 1 2022

Saving Billions of Lives with Next Generation CRISPR ...

Human & Planetary Health

News | Sep 30 2022

10 Questions with Arvind Gupta | BIOS

Human & Planetary Health

Viewpoint | Sep 26 2022

Enabling the Next Generation of CRISPR Products

Human & Planetary Health | News

News | Sep 21 2022

Cultured Meat Startup Prolific Machines Unveils its ‘Henry ...

Human & Planetary Health

Viewpoint | Sep 20 2022

CRISPR and the Precision Medicine Revolution

Human & Planetary Health

Viewpoint | Sep 14 2022

Founding Voices: Why a Shared Vision is Essential

Human & Planetary Health | Founding Voices

Viewpoint | Sep 14 2022

Five Insights From Investing in Prolific Machines

Human & Planetary Health

Viewpoint | Jun 8 2022

Saving our Planet One Sustainable Battery at a ...

Human & Planetary Health

Video | Jun 7 2022

Scientist Entrepreneurs — The Hard Truths of Scaling ...

Human & Planetary Health

Article | Jun 2 2022

Precision Immunology Platform Endpoint Health Raises $52M Series ...

Human & Planetary Health

News | May 17 2022

Mirvie Raises $60 Million For Blood Test To ...

Human & Planetary Health | News

Article | May 9 2022

Evolving from Scientist to Founder | TechCrunch Early ...

Human & Planetary Health | Company Building

Podcast | Mar 12 2022

Arvind Shares his POV on Climate Change & ...

Human & Planetary Health

Article | Feb 28 2022

Qventus Announces $50 Million Growth Capital Round

Human & Planetary Health

News | Jan 10 2022

Bayer and Mammoth Biosciences to Collaborate on Novel ...

Human & Planetary Health

News | Jan 5 2022

Study Published in Nature Shows Mirvie Can Predict ...

Human & Planetary Health

Podcast | Dec 3 2021

Silicon Valley Investment Trends | Startup Hustle

Human & Planetary Health

Viewpoint | Nov 16 2021

Healthcare Pioneers Share Secrets to Building Iconic Engineering ...

Conscious Capital | Human & Planetary Health

Viewpoint | Oct 17 2021

Health Innovator Summit Ebook

Human & Planetary Health

Article | Oct 15 2021

A Road Map for Climate Investors

Conscious Capital | Human & Planetary Health

Article | Oct 5 2021

Saving the World with BioNTech CEO Ugur Sahin ...

Human & Planetary Health

Video | Oct 4 2021

Rewiring the Brain to Improve the Quality of ...

Human & Planetary Health

Video | Oct 4 2021

Saving Lives with Precision Biology | Mayfield x ...

Human & Planetary Health

Video | Oct 4 2021

Taking Care of the Next Generation | Mayfield ...

Human & Planetary Health

Video | Oct 4 2021

The New Human and Planetary Health Pioneers | ...

Human & Planetary Health

Video | Oct 4 2021

Bioplatforms for Saving the Planet | Mayfield x ...

Human & Planetary Health

Viewpoint | Oct 4 2021

GraphWear: Solving a Holy Grail Problem to Save ...

Human & Planetary Health | News

News | Sep 9 2021

Mammoth Biosciences Achieves Unicorn Status with $195M Funding

Human & Planetary Health

Entrepreneur Journey | Sep 9 2021

Saving Billions of Lives with Next Generation CRISPR ...

Human & Planetary Health

Article | Aug 19 2021

Discover all things biotech with Mayfield at Disrupt ...

Human & Planetary Health

Podcast | Aug 2 2021

Synthetic Biology & The Biotech Revolution | BIOS

Conscious Capital | Human & Planetary Health

Video | Aug 2 2021

MedTech Insights with Salvatore Viscomi MD & Ursheet ...

Human & Planetary Health

Video | Jun 18 2021

5 Essential Moments in Building a Company

Human & Planetary Health | Company Building

Viewpoint | Jun 4 2021

The Startup Process for CPT Codes

Human & Planetary Health

Viewpoint | Jun 4 2021

Arvind Shares his Perspective on the Future of ...

Human & Planetary Health

Podcast | May 24 2021

Arvind Shares his Perspective on the SynBio Revolution

Conscious Capital | Human & Planetary Health

Article | Apr 27 2021

Mirvie Wants to Bring Liquid Biopsy Tech to ...

Human & Planetary Health | News

Video | Apr 26 2021

Scientist Entrepreneurs – Scaling Breakout Engineering Biology Companies

Human & Planetary Health

Viewpoint | Dec 9 2020

Engineering Biology: Five Silver Linings from 2020

Human & Planetary Health

Viewpoint | Nov 2 2020

Decoding the World: A Roadmap for the Questioner

Human & Planetary Health

Video | Oct 23 2020

Ursheet Shares Engineering Biology Investment Trends at SynBioBeta ...

Human & Planetary Health

Video | Oct 22 2020

Ursheet Shares his Perspective on Neuromodulation at SynBioBeta ...

Human & Planetary Health

Article | Oct 7 2020

Jennifer Doudna Wins Nobel Prize for CRISPR Discovery

Human & Planetary Health | News

Article | Sep 20 2020

Arvind Gupta’s Jiu Jitsu Makes Biotech Move at ...

Human & Planetary Health

Podcast | Aug 27 2020

Funding Biology with Conscious Capital to Save the ...

Conscious Capital | Human & Planetary Health

Article | Aug 13 2020

Mission Bio Raises $70M Series C

Human & Planetary Health | News

Viewpoint | Aug 1 2020

The $100 Trillion Opportunity

Human & Planetary Health

Podcast | Jul 26 2020

Designing Science with Arvind Gupta & Alex Lorestani

Human & Planetary Health

Viewpoint | Jul 15 2020

Investing in Human and Planetary Evolution

Conscious Capital | Human & Planetary Health | News

Viewpoint | Jul 13 2020

Endpoint Health: Partnering with Founders Building the Precision ...

Human & Planetary Health | News

Viewpoint | Jun 22 2020

The Secrets Behind Built-to-Last Companies

Human & Planetary Health

Viewpoint | Jun 22 2020

Three Post-Pandemic Areas of Opportunity in Digital Health ...

Human & Planetary Health

Viewpoint | Jun 22 2020

Portfolio Spotlight: Mammoth Biosciences

Human & Planetary Health

Viewpoint | Jun 10 2020

Engineering Biology Company Building

Human & Planetary Health | Company Building

Article | Jun 5 2020

Jennifer Doudna Shares How COVID-19 is Spurring Science ...

Human & Planetary Health

Video | May 19 2020

Evidence-Based Care, the Role of the AMA, and ...

Human & Planetary Health

Video | May 19 2020

Innovations in Care Delivery for Critical Conditions

Human & Planetary Health

Video | May 19 2020

The Secrets Behind Built-to-Last Companies

Human & Planetary Health

Video | May 19 2020

The Largest Post-Market Study on the Drugs that ...

Human & Planetary Health

Video | May 19 2020

The Role of the FDA in Enabling Healthcare ...

Human & Planetary Health

Article | May 13 2020

The New Diagnostics Marketplace in a Post-COVID-19 World

Human & Planetary Health

Video | Apr 14 2020

Create Capacity for COVID-19

Human & Planetary Health

Article | Apr 9 2020

Investing in Times of Turmoil, Neurotech and Happiness

Human & Planetary Health

Viewpoint | Apr 5 2020

Innovators Accelerating Delivery of COVID-19 Solutions

Human & Planetary Health

Article | Mar 13 2020

Qventus Offers a Solution for Hospitals to Predict ...

Human & Planetary Health

Viewpoint | Jan 30 2020

Enabling the Next Generation of CRISPR Products

Human & Planetary Health | News

Article | Dec 2 2019

Digitizing Biology and Scaling Precision Medicine Companies

Human & Planetary Health

Viewpoint | Sep 24 2019

Biology as Technology Will Reinvent Trillion Dollar Industries

Human & Planetary Health

Viewpoint | Jul 29 2019

Shaping the Future with Mission Bio’s Internship Program

Human & Planetary Health | Company Building

Article | Jul 23 2019

Synthetic Biology Investing in an Age of Open ...

Human & Planetary Health

Viewpoint | Jul 15 2019

Key Takeaways & Predictions from Health Evolution Summit ...

Human & Planetary Health

Video | Jun 11 2019

How to Create Jobs while Saving Lives

Human & Planetary Health

Article | Mar 5 2019

The Four Key Elements to Scaling Health IT ...

Human & Planetary Health | Company Building

Video | Jan 20 2019

Mammoth Biosciences CEO Trevor Martin & Ursheet Parikh ...

Human & Planetary Health

Viewpoint | Jan 15 2019

Accelerating Planetary Health

Human & Planetary Health

Video | Jan 2 2019

Designing Science with Arvind Gupta & Ursheet Parikh

Human & Planetary Health

Viewpoint | Dec 19 2018

The Biggest Threat to America is the Biggest ...

Human & Planetary Health

Article | Dec 13 2018

Mission Bio Raises $30 Million in Series B ...

News | Human & Planetary Health

Video | Oct 21 2018

Ursheet Parikh Shares Perspective on Precision Health

Human & Planetary Health

Viewpoint | Oct 3 2018

Building Synthetic Biology Companies at Scale

Human & Planetary Health | Company Building

Article | Sep 20 2018

Bio-Platforms: The Future of Innovation and Collaboration

Human & Planetary Health

Article | Jul 31 2018

Mammoth Biosciences Raises $23 Million for its CRISPR-based ...

Human & Planetary Health | News

Viewpoint | Jul 31 2018

CRISPR and the Precision Medicine Revolution

Human & Planetary Health | News

Viewpoint | Jun 19 2018

Healthcare Takes Center Stage At Mayfield Reception

Human & Planetary Health

Viewpoint | Dec 14 2017

Navin Chaddha on the Journey with Brighter

Human & Planetary Health | News | Enterprise

Viewpoint | Oct 12 2017

Mission Bio Delivers on the Promise of Precision ...

Human & Planetary Health | News

Viewpoint | Sep 18 2017

Ursheet Parikh Hosts Discussion on Digital Health Trends

Human & Planetary Health

Article | Jul 26 2017

A People-First View of Investing in Innovation

Enterprise | Consumer | Human & Planetary Health

Viewpoint | May 1 2017

Mayfield’s Ursheet and Tim Share Their POV on ...

Human & Planetary Health

Entrepreneur Journey | Mar 20 2017

Three Pivots to Better Healthcare

Human & Planetary Health | Gamechangers

Article | Mar 16 2017

Mayfield’s Parikh on What Makes Digital Health Startups ...

Human & Planetary Health

Viewpoint | Jan 9 2017

6 Reasons Why Digital Health Startups Will Fail

Human & Planetary Health | Company Building

Viewpoint | Jul 26 2014

Start-ups are finally hacking healthcare

Human & Planetary Health

Non-obvious Insights from Healthcare Innovators

Get a deep look at non-obvious insights from healthcare innovators, shared at previous Mayfield gatherings.

Investments

Lyft logo

NASDAQ: LYFT | Partnered Early

NASDAQ: POSH / Acquired by NAVER | Partnered at Inception

Partnered at Inception

NASDAQ: SCTY / Acquired by Tesla | Partnered Early

NASDAQ: AMGN

Former NASDAQ: APPB

Acquired by Intel | Partnered at Inception

Acquired by Cigna | Partnered at Inception

Partnered at Inception

Partnered at Inception

Partnered Early

Former NYSE: GENE

GraphWear logo

Partnered Early

Acquired by HP

NASDAQ: ISRG

Millenium Pharmaceuticals logo

Former NASDAQ: MLNM

Partnered Early

Partnered Early

Partnered at Inception

Partnered Early

Tripp logo

Partnered at Inception

Partnered at Inception

Human & Planetary Health Team

Ursheet Parikh

Ursheet Parikh

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Ursheet Parikh

Ursheet Parikh

Ursheet invests in Infrastructure Software and Human & Planetary Health.

His investments in the enterprise sector include Versa Networks (Security and SD-WAN), Qwiet (Application Security), Rancher Labs (Cloud Computing platform acquired by SUSE), CloudGenix (SD-WAN platform acquired by Palo Alto Networks) and Netsil (Application Observability platform acquired by Nutanix).

Ursheet’s investments in human & planetary health include Mammoth Biosciences (CRISPR), Mission Bio (Single Cell Sequencing, Oncology), Qventus (Healthcare AI), Endpoint Health (Precision Immunology), Mirvie (predict and prevent pregnancy complications for moms and babies), GraphWear (Continuous Non-invasive Glucose Monitoring), Chemix (AI-powered next gen EV battery technologies) and Foodsmart (reverse metabolic disease).

Prior to Mayfield, Ursheet had an operating career as a repeat entrepreneur and executive at Cisco and Microsoft. Ursheet was co-founder & CEO of StorSimple – the leading cloud-integrated storage company that was acquired by Microsoft in 2012.

Ursheet holds an MBA from the Wharton School and a Bachelors in Computer Science from the Indian Institute of Technology in Mumbai, from which he received the Young Alumni Achiever award in 2015.

Ursheet is passionate about accelerating healthcare innovation and transforming college education where his family foundation is focused.

Full Bio
Arvind Gupta

Arvind Gupta

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Arvind Gupta

Arvind Gupta

Arvind Gupta focuses on investments in Human & Planetary Health where his mission is to invest in science based companies that could change history. Ranging from reinventing our food system to stopping climate change to novel therapeutics, Arvind was the first investor in breakout companies such as Geltor,Synthex, Prime Roots, NotCo, Prellis, New Culture, DNA Lite, Catalog, Prellis and Memphis Meats.

As Founder of IndieBio, Arvind redefined the pace and possibilities of early stage biotech, investing in over 136 companies in five years, defining human and planetary health, and growing the IndieBio portfolio into billions of dollars in value. Under his leadership, IndieBio expanded to New York and grew to fifteen investment professionals with a world renowned adjunct partner board. He now serves as Venture Advisor at IndieBio.

Arvind is the author of Decoding the World: A Roadmap for the Questioner, published by Twelve Books, a division of the Hachette Publishing Group. He was honored with the F50 Global Award for Impact in HealthTech Innovation. He is a frequent speaker at TechCrunch Disrupt, Slush, TedX and Future FoodTech. His work has been profiled in global media outlets such as Bloomberg News, Forbes, The Guardian UK, Neo.life, Nikkei News, Rotman, The Times of India, and CGTN in China. Arvind has been a guest lecturer at UCSF, MIT and Harvard and is a judge at the annual BIO conference startup stadium.

Prior to founding IndieBio, Arvind was Design Director at IDEO in Shanghai where he earned numerous international design awards and presented his work at the San Francisco Museum of Modern Art. He was also a BASE jumper and big wall climber and now fights professional grappling.

Arvind received his B.S. in Genetic Engineering from UCSB. He holds 8 patents.

Arvind is married to an Icelander and has two daughters.

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Navin Chaddha

Navin Chaddha

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