AI + Human = Human²

We believe that two dynamics will combine to establish AI as a powerful force. First, our main form of interacting with computing devices will change. It will become conversational. The impact of that change will be compounded by a second one: for the first time, technology will be able to perform cognitive tasks that augment our own capabilities. The result is that we’ll be able to multiply our own capabilities with a human-like teammate, or assistant, or genie. AI + Human = Human² , as in Human Squared. We think the industry is going into a deeper sea change — the era of Cognition-as-a-Service (CaaS) — which follows the mega waves of IaaS (Infrastructure-as-a-Service), PaaS (Platform-as-a-Service) and SaaS (Software-as-a-Service). We invest in AI-first companies across the six layers of the CaaS stack.

Where We’re Investing

CaaS

Mayfield Start Logo

Providing Mentor Capital
to AI Founders Starting at Day Zero

Mayfield has a long history of championing entrepreneurs on their inception to iconic journeys. We believe in serving as trusted partners to entrepreneurs at every stage and are guided by a set of operating principles that we call The Mayfield Way. We know that AI-First teams have unique needs and have designed programs and services that meet you where you are. Our $250 million AI Start fund partners with entrepreneurs starting at Day Zero, when often all you just have is an idea.

We like to be the first institutional check in for $1-4 million, investing in startups across the six layers of the Cognition-as-a-Service stack, primarily on the West Coast. Calling all builders, even pre-product. Read more here.

Investments

Partnered Early

Partnered Early

Seekout Logo

Partnered at Inception

Partnered Early

Partnered at Inception

Partnered at Inception

Partnered at Inception

Partnered Early

DevRev logo

Partnered at Inception

DuploCloud Logo

Partnered Early

Partnered at Inception

Partnered at Inception

Partnered Early

Partnered Early

NeuBird AI logo

Partnered at Inception

Partnered Early

Partnered Early

Partnered at Inception

Partnered at Inception

Partnered at Inception

Versa Networks logo

Partnered Early

Our Perspective

E-Book | Jun 11 2024

AI: A 100x Force Transforming Our Lives

AI

Viewpoint | May 17 2024

Mayfield CXO Insight Call – LLM Application Observability ...

CXO of the Future | AI

Viewpoint | May 3 2024

How Hard Can It Be? Lessons from Jensen ...

Company Building | AI

Viewpoint | Apr 17 2024

Embrace the Future: Meet Your AI Teammates

AI

Viewpoint | Apr 17 2024

Fund/Build/Scale: Understanding Privacy and Compliance (Transcript)

Company Building | AI

Viewpoint | Mar 29 2024

Practical AI: Early Use Cases in the Enterprise ...

CXO of the Future | AI

Viewpoint | Mar 1 2024

Cognition-as-a-Service (CaaS): The Rise of Digital Assistants & ...

AI

Viewpoint | Feb 23 2024

Learnings from Leaders: Satya Nadella/Microsoft

Company Building | AI

Podcast | Feb 6 2024

Fund/Build/Scale: Navin Chaddha on Building Trust with Your ...

Company Building | AI

Podcast | Feb 5 2024

Understanding Privacy and Compliance

AI | Fund-Build-Scale

Viewpoint | Feb 2 2024

World Economic Forum: How AI Can Usher In ...

AI

Viewpoint | Jan 31 2024

The Rise of the AI Cognitive Plumbing Layer

Enterprise | AI

News | Jan 29 2024

A People-First View of the AI Economy

AI | Hide

Viewpoint | Jan 29 2024

Partnering with Sema4.ai to Accelerate the Agent Economy

Enterprise | AI

Viewpoint | Jan 23 2024

Top 10 Takeaways From Davos

AI

Video | Jan 23 2024

“No Rain, No Flowers: Funding Start-ups” Lessons From ...

AI

Viewpoint | Dec 7 2023

Navigating the Good, the Bad, the Ugly of ...

AI

News | Nov 7 2023

An Investor and a Practitioner’s Perspective on GenAI

AI

Viewpoint | Nov 6 2023

Ursheet Parikh: Investing Ethically in AI and Synthetic ...

Human & Planetary Health | AI

Viewpoint | Nov 2 2023

LLM-powered Developer Automation

AI

Viewpoint | Oct 2 2023

From Inception to Iconic: What it Takes to ...

Company Building | AI

Viewpoint | Sep 29 2023

Navin Chaddha: Helping Entrepreneurs Achieve Their Dreams

Enterprise | Company Building | Semiconductors | AI

Viewpoint | Sep 29 2023

What AI Will (& Won’t) Do: AI Predictions ...

AI

Viewpoint | Sep 26 2023

Accelerating GenAI Adoption Through a Data Operations Cloud

Enterprise | AI

News | Aug 30 2023

A People-First View of the AI Economy | ...

Company Building | AI

Viewpoint | Aug 9 2023

5 Questions Investors Should be Asking Inception-stage Generative ...

Enterprise | Company Building | AI

News | Jul 20 2023

Mayfield Announces $250 Million AI Start Seed Fund ...

News | AI

News | Jul 20 2023

Mayfield Launches New $250 Million AI-Specific Seed Stage ...

News | AI

News | Jul 20 2023

Announcing The $250 Million Mayfield AI Start Seed ...

News | AI

Viewpoint | Jun 30 2023

GenAI in the Developer Landscape

CXO of the Future | AI

Viewpoint | Jun 21 2023

Silicon Catalyst – Fireside Chat with Navin Chaddha

Enterprise | Company Building | Semiconductors | AI

Viewpoint | Jun 1 2023

MindsDB: Introducing the World’s First Cloud to Serve ...

Enterprise | News | AI

Viewpoint | Mar 31 2023

Generative AI and the Future of Artificial Intelligence

CXO of the Future | AI